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  • 2024/11/21 18:33
• New study shows promise for analyzing interstitial cystitis/ bladder pain syndrome
  
  

  Interstitial cystitis, also known as bladder pain syndrome, is a debilitating disease of the urinary bladder. The disease can occur with or without bladder ulcers (called Hunner lesions). Interstitial cystitis is a difficult disease to study because animal models are limited, and human patients cannot ethically be subjected to invasive research procedures.

   

  The researchers' goal was to develop a noninvasive method to analyze the bladder epithelium as objectively and directly as possible. During the study, the researchers used microarray technology to analyze cells shed into the urine as an alternative to bladder biopsies, which require anesthesia and have a small risk of bladder injury.

   

  The results showed that urine cells from patients with Hunner lesions had a distinct gene signature for inflammation, similar to the results from a prior microarray study of bladder biopsies. The study was the first to show this inflammation objectively, but without biopsy, in Hunner lesion patients.

   

  If these preliminary results are validated in future research, they may lead to a noninvasive biomarker for Hunner lesion-interstitial cystitis/bladder pain syndrome, says researcher Eric Blalock, associate professor in the Department of Molecular and Biomedical Pharmacology at the UK College of Medicine.

   

  "A crucial next step will be to determine the stability of this set of biomarkers across larger samples of the population," Blalock said. "And to also see if similar procedures could be used for early diagnosis and intervention in the disease process."

   

  For interstitial cystitis patients without Hunner lesions, the gene signatures were similar to healthy controls.

   

  "This is important in view of the ongoing debate whether the two types of interstitial cystitis really are different disorders," said UK urologist Deborah Erickson. "Prior studies showed the two patient types did have different findings on bladder biopsies. Our findings support the difference, but without the need for biopsy."

   

  The study was published in the February issue of the Journal of Urology and was also selected for post-publication in the Faculty of 1000 (F1000), a global peer review group that identifies and evaluates the most important articles in biology and medical research publications. Selection places a researcher's work in F1000's library of the top 2 percent of published articles in biology and medicine.

  Provided by University of Kentucky

  Article Source: http://www.diureticspill.com/News/2012/0320/cystitis.html

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  • fukushow
  • 2014/07/23 14:29
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• Distinguish uterine fibroid from uterine sarcoma
  Many people do not understand the difference between uterine fibroid and uterine sarcoma. And they always confuse these two diseases which however, have essential distinctions.

   

  Uterine fibroid:

   

  It is the most common benign tumor of females (having a higher incidence in women aged 30-50). According to ultrasound evidence, 70% in white women and 80% in black women are estimated to run the risk of uterine fibroid. 

   

  Uterine fibroid forms mainly due to the uterine smooth muscle cell proliferation. So the exact name of uterine fibroid should be uterine leiomyoma. And because of its pathogenesis is female hormones (estrogen and progestogen) related, therefore, it attributes to hormone dependent tumor.

   

  Patients with uterine fibroid have no obvious symptoms. This disease can be only accidentally discovered in the gynecological examination or surgery. Patients can have menstrual changes (increased menstrual blood volume, shorter menstrual cycles or menstrual extension, irregular bleeding, and so on), pain (seldom appears, but acute abdominal pain occurs when fibroid has red degeneration or submucosal fibroid is stimulated, and consequently cause uterine spasmodic contraction), oppression symptoms (fibroid oppressing bladder causes urinary frequency, voiding dysfunction and urinary retention, and oppressing ureter can be lead to hydronephrosis), increased vaginal discharge, infertility, anemia (long-term menorrhagia can lead to secondary anemia).

   

  Uterine sarcoma:

   

  It is a malignant female genital tumor, and is rare (3 to 7 per 100,000 in the United States population).

   

  Uterine sarcoma accounted for 2% of uterine malignant tumors, and the onset is about 50 years old age. The main clinical manifestations include: abnormal vaginal bleeding (postmenopausal vaginal bleeding or menstrual abnormalities), abdominal mass, abdominal pain (due to the rapid growth of myoma), increased vaginal secretions (serous, hemorrhagic or white, with purulent or stench). The incurably ill patients can have symptoms like emaciation, anemia, fever, and so on.
  
  Conclusion:

   

  All in all, uterine fibroid is rare malignant translated, and patients can take oral patent medicine Fuyan Pill to eradicate it. The uterine sarcoma patients, however, need to receive surgical treatment according to the specific situation. And if it is necessary, patients should receive chemotherapy, radiation therapy, or herbal treatment to cooperate with surgeries.

  
  

  Article Source:  http://www.drleetcmclinic.com/a/Blog/2014/0510/185.html
  • fukushow
  • 2014/07/18 17:21
  • 0
• Four effective treatments for benign prostatic hyperplasia patients
  
  

  Benign prostatic hypertrophy commonly refers to benign enlargement of the prostate (BEP). It is especially prevalent in older men aged over 45-60. Clinically, untreated prostatic hyperplasia will bring much harm to men, such as fibrosis of prostate, calcified prostate, and it can even cause male infertility. Thus, it is crucial for men to know its proper and effective treatment.

   

  Generally, there are four treatment options: vigilance observed, western drugs, surgery and TCM therapy.

   

  1. Vigilance observed is generally for diagnosing prostatic hypertrophy patients. It can observe the patients' conditions to take some corresponding physical treatment. Thus, it has no therapeutic effect, only for nursing of the disease.

   

  2. Western drugs can indeed relieve some symptoms of the disease. However, the drugs have many side effects and patients are easy to develop drug resistance, even cause damage immune system. Besides, some western medicine is only used to relieve symptoms, but it cannot entirely clear the pathogenesis. Therefore, drug treatment is not a proper treatment for prostatic hyperplasia.

   

  3. Surgical treatment is mainly for bilateral testis orchiectomy, transurethral resection of the prostate and some other palliative surgery. However, the surgery has high risks and it costs a lot. 

   

  4. Traditional Chinese medicine (TCM) treatment is aimed at comprehensive conditioning and thoroughly curing the disease. Although it needs a relatively long period of time, but the effect is good and the relapse rate is low.

   

  In a view, if surgery or medical therapy cannot cure the disease entirely, patients can try the TCM treatment like taking diuretic and anti-inflammatory pill. The herbal pill is made of Plantago seed, Dianthus superbus, Talc, Earthworm, Seaweed, Pangolin, Safflower, Honeysuckle, Houttuynia, Gardenia, Scutellaria Baicalensis, Amomum, Cowherb Seed, Woody, Magnolia, Citrus aurantium and some other herbs. 

   

  The herbal pill not only can improve the obstructive symptoms and relieve frequency and urgency in patients, but also has good effect on reducing the proliferation of prostatic hypertrophy. Patients can achieve complete cure within 1-3 months' treatment.  

  
   

  Attention

  It is worth recalling that for patients with abnormal hypertrophy, if it is scope of surgery treatment, they can also take diuretic anti-inflammatory pill to promote healing after the surgery.

  
  

  Article Source:  http://www.drleetcmclinic.com/a/Blog/2014/0524/190.html
  • fukushow
  • 2014/07/18 17:20
  • 0
• 2013秋冬新作 人気が爆発 TORY BURCH トリーバーチ偽物バングル

  2013秋冬新作 人気が爆発 TORY BURCH トリーバーチ偽物バングル

  • 商品番号：KOPI2013SZ-TORY019
  • 品　　番：KOPI2013SZ-TORY019
  • ブランド：TORY BURCH トリーバーチ

  

   

  KOPI- BURANNDO(コピーブランド)はブランド コピー 激安通販専門店、当店はブランド服コピー、ブランドバッグコピー,スーパーコピー 財布,スーパーコピー 時計が提供します,全で新品、業界最高品質（N級品）本物と真似た偽物?模造品?複製品です。激安価格！品質を重視し、納期も 厳守し、信用第一を当社の方針にしています。安心してご購入ください

  • fukushow
  • 2014/06/27 11:04
  • 0
• 2013秋冬新作 高級☆良品 TORY BURCH トリーバーチ偽物 バングル

  2013秋冬新作 高級☆良品 TORY BURCH トリーバーチ偽物 バングル

  • 商品番号：KOPI2013SZ-TORY004
  • 品　　番：KOPI2013SZ-TORY004
  • ブランド：TORY BURCH トリーバーチ
  • 

   

  KOPI- BURANNDO(コピーブランド)はブランド コピー 激安通販専門店、当店はブランド服コピー、ブランドバッグコピー,スーパーコピー 財布,スーパーコピー 時計が提供します,全で新品、業界最高品質（N級品）本物と真似た偽物?模造品?複製品です。激安価格！品質を重視し、納期も 厳守し、信用第一を当社の方針にしています。安心してご購入ください

  • fukushow
  • 2014/06/27 11:02
  • 0